Technically anything that ticks works well with enervation. My choice of pyro is plainly to add more skills into my rotation , say for CM. Even w/o joint-knot I can still use enervation+ flame ground to deal damage
Blood curse removes 80% of your HP, and I rely on fireball to heal it up since it’s AOE it’s rather huge
Unless you are wiz 2 I don’t recommending getting very high lvl for blood suck. Damage is around 11k per tick , more than succificient to heal yourself up in 2-3 ticks.