Well okay, I actually have two characters level 210. One being high SPR build, the other not.
With my SPR character, debuffs don’t bother me that much cause he has around 80% chance to resist most of them.
With my no-SPR character, sometimes a really bad debuff like petrification will hit me and if theres a large number of mobs after me they’ll rape me. Of course it’s annoying to die and all, but I’d rather pay the cost to repair my gears (~10k) every now and then in a rare occasion where a really bad combo hits me than pay 50 dispeller scrolls (~25k) every hour to block 99% of random debuffs that won’t be that harmful to my character at all (stuff like silence, blind, poison, etc).
Like I said, debuffs are generally not very harmful in PvM. When they do harm, you’re usually not expecting it. And it’s not cheap keeping dispellers 100% up during PvM.
But yeah, if you know what you’re dealing with, and you know that certain mob doesn’t have any debuffs, you can trigger dispellers off to save them, and trigger them on against mobs with annoying debuffs.