This is not a new issue.
In fact it is more than unresolved.
There are quest objectives such as items, doors, portals, NPCs, and any number of other things that are usually interacted with using the Controller or Keyboard that are absolutely impossible to trigger with the mouse.
These objectives have been exactly like this for months, some of them ever since CBT1.
I have seen nearly every one of these reported in the past also, this is absolutely not a recent revelation.
It’s just sloppy to stay like this.