As there are more and more Sages nowadays, most of them will buff you with Missile Hole, which is a completely unneccessary buff in PVE in over 90% of the cases.
However, as it is a 1st column buff and thus affecting the total bufflimit of your character, I believe it’s injust to make the buff unremoveable by right-clicking on the buff icon, so please make the buff removeable.