The Alchemist skill “Magnum Opus” does not incorporate ingredients into any recipes if the materials being used are specific to the Orsha “side” as well as the maps beyond (what appears to be) the lvl200 range.
Basically… Magnum Opus has not been worked on or updated to match the current game and has been instead left abandoned since icbt2. Materials gathered from post-icbt2 additions such as Orsha specific maps as well as more recent content have been excluded from any functionality within Magnum Opus.
This is correctly being addressed as a bug, and not a feature request, because a largely incomplete skill cannot remain in such a state when compared to much more complete and current content.
Expected Result: Magnum Opus should be updated to reflect the current content players may experience. Possible recipes need to be updated beyond the Klaipeda starting “side” and Fedimian maps. Future content updates include additional updates to the skill to maintain relevancy.