Your stats basically depend on what you’re willing to invest in time/silver on that character.
As a Plague Doctor, you don’t really need any CON, a little CON can be gained easily with the new random stat gears and a good shield.
STR/DEX won’t be necessary either, so the question is about INT and SPR investment.
Depending on how much you’re willing to spend, you can gain the ~200 SPR to maintain your build while spamming Effigy/Damballa with equipment or actually invest ~92 points (so you have 100 base SPR) into SPR and focus more on getting extra CON&INT from equipment.
If you want the extra matk or not solely depends on your investment&choice, the more you spend on transcending the weapon, the less the impact of non-invested INT becomes in terms of matk and the more you might want to spread your points for more convenience.