I finally killed the 3m hp boss from the murmillo quest took me 2 hours and 40 minutes. My set for the quest were, full grynas plate set, magas sword, and didel tower shield. My class is swordman c1 peltasta c3 squire c3 and my stats are 2 con for 1 str.
As i said it took me 2 hours and 40 minutes ( it coulnd be less if u bring enoguth potions) so these are my tips for you to be a little bit easier.
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Bring 100 or 200 potions of hp lvl 15 (from alchemist) just to be safe
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Be prepared , get the 3 buffs from the best pardoner you can find, dont waste your time asking for normal buffs, its long fight they will fade off fast.
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Also if you are squire c3 buff your weapon you will need the extra damage and try to repair your self at least the weapon for 15 extra durability.
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The boss use 3 tipes of attacks, a normal attack aoe in front of him, a smash ground only aoe in front and at his sides and the last attack ( the more annoying one) the scream, he will scream at aoe all arround him and then hit the ground , 2 attacks in quick succession .
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This is how i killed him, the normal attack is easy to avoid just hit 2 with normal attack then move to one of the sides of him and keep doing it until he changes the attack, if he hit the ground, again stay in his back u can hit 3 times if u are fast, the last one is the scream , you can try to avoid it but its hard , the best thing you can do its block it with manual block ( C key) when you block both attacks ( screem and the ground smash) u can easily do 2 umbo blows before he turn arround.
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If u runout of potions try to you use your pet againts it to win some time for you to rest on a fire, just a few seconds will do.
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DO NOT give up, its a long fight ( i know it) your weapon at the end it will start to break but keep fighting.
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Belive it or not its a usefull tip, so , make sure you are not bother by anything for the next couple of hours ( yes thats right , use the bathroom if you have to, eat, bath, talk to your girlfriend / boyfriend, everything before you set for this quest)
Thats it , good luck and NEVER GIVE UP NEVER SURRENDER.
Sorry for my crappy english

. I personally would’ve fallen asleep.
. Tank specs are always going to have trouble killing no matter the game. For comparison, it took me 10-15mins to kill that boss. It would’ve been even faster if I wasn’t minus 10 levels. It did take me a few deaths to work out his pattern though but once I got the hang of it, it was fairly straightforward.